Epithalon (also known as Epithalamin) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally derived from the pineal gland. It has been widely studied for its potential roles in cellular longevity, telomerase activation, and systemic anti-aging effects in preclinical and clinical research.

Epithalon has been studied for its ability to:

 Activate telomerase, the enzyme that helps maintain and lengthen telomeres — a key marker associated with cellular aging.
 Support cellular longevity by improving genomic stability and reducing replicative senescence.
 Promote antioxidant defenses and reduce oxidative stress markers in preclinical models.
 Support pineal gland function, potentially influencing circadian rhythm regulation and melatonin secretion.
 Modulate immune system activity, aiding in balanced immune responses in aging research.